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Session 5: Neural Stem Cells - KEYNOTE - Lawrence Goldstein

The zebrafish brain continues to add new neurons throughout life, and unlike humans, the zebrafish brain and spinal cord have amazing regenerative capacity. We are trying to understand what regulates the stem cell proliferation needed for this life-long growth and healing. Disruption of these processes can lead to tumors in humans, thus an understanding of the mechanisms of regulating cell proliferation in zebrafish promises to impact our understanding of human cancers.

Microglia & Neural Stem Cell Differentiation | Applied StemCell

Overall, the student will learn how the zebrafish can be used as a model organism to study developmental and disease processes that are similar across vertebrate species, including humans. Learn more. Apply Now. Links to common UMass Amherst services and features. In particular, the possibility of extracting neural stem cells from the blood of patients without invasive intervention is a decisive advantage for future therapeutic approaches. What is special about the reprogrammed cells of the Heidelberg researchers is that they are a homogeneous cell type that resembles a stage of neural stem cells that occurs during the embryonic development of the nervous system.

The iNBSCs of the Heidelberg scientists are expandable and multipotent and can develop in two different directions. On the one hand, they can take the path of development to mature nerve cells and their supplier cells, the glial cells, i. On the other hand, they can also develop into cells of the neural crest, from which different cell types emerge, for example peripheral sensitive nerve cells or cartilage and bones of the skull.

Neural Development and Stem Cells

The iNBSCs thus form an ideal basis for generating a broad range of different cell types for an individual patient. However until we can use them in patients, a lot of research work will still be necessary," emphasizes Trumpp. Note: material may have been edited for length and content. For further information, please contact the cited source.

Neural Development & Regeneration

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A new study has shown the power of genetic testing to pick out the best drugs for children with cancer to extend and improve their lives — signalling a new era of precision medicine for young patients. Scientists have discovered that a certain protein, which is more prevalent in older people, interferes with bone healing. Like what you just read?

Identification of Neural Stem Cells

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